• Mw: 60 kDa + glycans
• Tags: C-terminal Avi-Tag™
• Format: Aqueous buffer solution.
• Purity: ≥90%
• Genbank: NM_005618.4
• Species: Human
• Uniprot: O00548
• Shiptemp: -80°C (dry ice)
• Synonyms: Drosophila Delta homolog 1 (Delta1; H-Delta-1), Delta-like protein 1
• Warnings: Avoid freeze/thaw cycles
• Category: Cell Signaling/Protein
• Background: DLL1 is involved in cell-to-cell communication and in embryonic development, neurogenesis, and tissue homeostasis. It is a member of the Delta-Serrate-Lag2 (DSL) family of ligands that activate the Notch signaling pathway. DLL1 binds to the Notch receptors on neighboring cells, triggering signals that regulate cell fate determination, proliferation, and differentiation. Dysregulation of DLL1 has been implicated in several diseases.
• Description: Recombinant human DLL1 (delta like canonical Notch ligand 1), encompassing amino acids 18-540. This construct contains a C-terminal Avi-Tag™ followed by a His-tag (6xHis). The recombinant protein was affinity purified.
• Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Host Species: Human
• Product Type: Protein
• Host Cell Line: HEK293
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 40595, 100413, 45100, 100413
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Cell Signaling Pathway
• Instructions for Use: Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles.

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