Recombinant Murine KGF (FGF-7)

DESCRIPTION

KGF (FGF‐7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth, and the regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF (FGF‐7) is a mitogen factor specific for epithelial cells and keratinocytes. KGF/FGF‐7 signals through FGFR 2b. KGF (FGF‐7) plays a role in kidney and lung development, as well as in angiogenesis and wound healing. Recombinant Murine KGF (FGF‐7) is an 18.8 kDa protein consisting of 164 amino acid residues.

DETAILS

Gene Id: 14178
Uniprot: P36363
Activity: Determined by a cell proliferation assay using 4MBr-5 cells. The expected ED50 for this effect is 0.5-5.0 ng/ml
Category: RUO Cytokines
Subcategory: Growth Factors & Cytokines
Research Areas: Angiogenesis/Cardiovascular, FGF Superfamily, Immune System, Stem Cells and Differentiation, Wound Healing, Diabetes/Weight Regulation
Alternative Names: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7
Species of Origin: Murine
Expression System Source: E.coli