PhotoSericin is 1 gram of lyophilized, sterile, methacrylated sericin. PhotoSericin provides 3D hydrogels with the unique attributes to be prepared at various concentrations and photocrosslinked (requires a photoinitiator) to provide various gel stiffness. PhotoSericin is a highly versatile solution designed for researchers and scientists seeking advanced materials for tissue engineering, drug delivery, and regenerative medicine applications. PhotoSericin provides 3D tunable gels with the unique attributes to be prepared at various concentrations and crosslinked to provide various gel stiffnesses. PhotoSericin is also offered in convenient kits that include a selected photoinitiator, provided separately as a powder to provide customization and precise control over the crosslinking process.