DESCRIPTION

• Aa: 26-161
• Mw: 41.2 kDa
• Tags: C-terminal Fc fusion (Human IgG1)
• Notes: The aggregation state of this product has been confirmed to be <10%.
• Format: Aqueous buffer solution
• Genbank: NM_004195
• Species: Human
• Uniprot: Q9Y5U5
• Shiptemp: -80°C (dry ice)
• Synonyms: Glucocorticoid-induced TNFR-Related Protein, Tumor Necrosis Factor Receptor Superfamily member 18, TNFRSF18, Activation-Inducible TNFR Family Receptor, AITR, CD357
• Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
• Category: Immunotherapy/Protein
• References: 1. Shimizu, J., et al., Nat. Immunol. 2002; 3: 135-142. 2. Ko, K., et al., J. Exp. Med. 2005; 202(7): 885-891.
• Description: Human secreted GITR, Fc fusion protein, also known as Glucocorticoid-induced TNFR-Related Protein, Tumor Necrosis Factor Receptor Superfamily member 18, TNFRSF18, Activation-Inducible TNFR Family Receptor, AITR, and CD357, GenBank Accession No. NM_004195, a.a. 26-161 expressed in a HEK293 cell expression system. MW = 41.2 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
• Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for studying protein binding and screening small molecular inhibitors
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Endotoxin Level: <1 EU/µg
• Related Products: 71170, 71190
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Immunotherapy