12-9366
Anti-NEFL(9-88) antibody(DM198), Rabbit mAb
Abeomics
DESCRIPTION
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
DETAILS
- App Id: ELISA,FACS
- Antigen: NEFL
- Format Id: Liquid
- Clone Name: DM198
- Host Animal: Rabbit
- Clonality Id: Monoclonal
- Purification: Purified from cell culture supernatant by affinity chromatography
- Reactivity Id: Human
- Alternative Name: CMT1F; CMT2E; CMTDIG; NF-L; NF68; NFL; PPP1R110
- Application Note: ELISA 1/5000-10000;FACS 1/100
- Storage Condition: Store at -20°C for 12 months (Avoid repeated freezing and thawing)