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EHNA hydrochloride
Biogems
DESCRIPTION:
EHNA is a potent adenosine deaminase and phosphodiesterase type 2 inhibitor. It is reported to be used to inhibit spontaneous differentiation of stem and neuronal cells.
DETAILS
- Purity: ≥98%
- Synonyms: NSC263164, EHNA HCl, Adenosine deaminase inhibitor, 9H-Purine-9-ethanol, monohydrochloride
- Cas Number: 58337-38-5
- References: Baker, D. C., Hanvey, J. C., Hawkins, L. D., & Murphy, J. (1981). Identification of the bioactive enantiomer of erthro-3-(adenin-9-YL)-2-nonanol (EHNA), a semi-tight binding inhibitor of adenosine deaminase. Biochemical pharmacology,30(10), 1159-1160. Woodson, J. C., Minor, T. R., & Soames Job, R. F. (1998). Inhibition of adenosine deaminase by erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) mimics the effect of inescapable shock on escape learning in rats. Behavioral neuroscience, 112(2), 399. Burton, P., Adams, D., Abraham, A., Allcock, R., Jiang, Z., McCahill, A., ... & Mountford, J. (2010). Erythro-9-(2-hydroxy-3-nonyl) adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells. Biochem. J, 432, 575-584.
- Application: FA
- Formulation: Crystalline solid
- Chemical Name: (2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol;hydrochloride
- Molecular Weight: 313.8
- Molecular Formula: C14H23N5O HCl
- Storage Conditions: Product should be kept at -20°C.
- Pubchem Openeye Can Smiles: CCCCCCC(C(C)O)N1C=NC2=C(N=CN=C21)N.Cl