CDK5R2(p39) Antibody (N-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 8941
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: CDK5R2
Other Names: Cyclin-dependent kinase 5 activator 2, CDK5 activator 2, Cyclin-dependent kinase 5 regulatory subunit 2, p39, p39I, CDK5R2, NCK5AI
Availability: 2 weeks
Bio Background: CDK5R2(p39) is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins.
Bio References: Rademakers,R., Neurobiol. Aging 26 (8), 1145-1151 (2005)Dhavan,R., J. Neurosci. 22 (18), 7879-7891 (2002)Patzke,H., J. Biol. Chem. 277 (10), 8054-8060 (2002)
Primary Accession: Q13319
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7742a was selected from the p39 region of human CDK5R2(p39). A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.