#60037
DPA
Biotium
DESCRIPTION
Dipicrylamine (DPA) is a nonfluorescent anionic membrane dye. With its absorbance in the blue region of the visible spectrum, DPA can be used as a FRET quencher for a variety of fluorescent donor dyes. When applied to cells, DPA localizes at the interface of cytoplasmic membrane and aqueous phase in a manner sensitive to membrane potential change. A recent application of DPA is to measure cell membrane potential change by combining with the fluorescent donor dye DiOC16. The DiO/DPA system has been reported to produce a fluorescence signal change of >56% in HEK-293 cells and >25% in neuronal cultures and brain slices per 100 mV membrane potential change. Please also see the DiO/DPA Membrane Potential Detection Kit. Yellow solid soluble in DMSO at >30mg/mL &lamba;abs (MeOH) = 406 nm Store at 4°C MWt: 439.21 [131-73-7]
DETAILS
- Cas Number: [131-73-7]
- Product Origin: Synthetic
- Product Categories: Cell & Organelle Stains>Membrane Potential & Nerve Terminal Dyes