Human ADAM8 / CD156a Protein, His Tag

DESCRIPTION

Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.

DETAILS

Tag: C-6×His
Host: HEK293
Size: 500ug
Buffer: 50 mM Tris, 150 mM NaCl, pH7.5
Format: Powder
Purity: 90%
Source: Human ADAM8, His Tag (AD8-H5223) is expressed from human 293 cells (HEK293). It contains AA Ile 17 - Pro 497 (Accession # AAI15405.1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: ADAM8
Accession: AAI15405.1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Ile 17 - Pro 497
Swiss-prot: P78325-1 (W35R)
Package Size: 250ug*2
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53.8 kDa. Two main fragments bands are visible with apparent MW of 57-65 kDa and 35-40 kDa respectively in reduced SDS-PAGE as a result of its being prone to proteolytic cleavage.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 53.8 kDa
Shipping Condition: RT
Species Reactivity: Human
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