Anti-Aldolase Antibody [JM54-19]

DESCRIPTION

Fructose 1,6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1,6-bisphosphate. Fructose 1,6-bisphosphate aldolase exists as three forms: the muscle-specific Aldolase A; the liver-specific Aldolase B; and the brain-specific Aldolase C. Aldolase A, B and C arose from a common ancestral gene from which Aldo-lase B first diverged. Aldolase A is one of the most highly-conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon, and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.

DETAILS

Host: Rabbit
Type: Primary
Uniprot: SwissProt: P04075 Human;SwissProt: P05064 Mouse;SwissProt: P05065 Rat
Clone Id: JM54-19
Clonality: Recombinant Rabbit monoclonal Antibody
Conjugate: Non-conjugated
Alias Names: ALDA antibody Aldo1 antibody ALDOA antibody ALDOA_HUMAN antibody Aldolase 1 antibody Aldolase A antibody Aldolase A fructose bisphosphatase antibody Aldolase A fructose bisphosphate antibody Aldolase, fructose-bisphosphate A antibody Epididymis secretory sperm binding protein Li 87p antibody FRUCTOALDOLASE A antibody Fructose 1 6 bisphosphate triosephosphate lyase antibody Fructose bisphosphate aldolase A antibody Fructose bisphosphate aldolase antibody FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE A antibody Fructose-bisphosphate aldolase A antibody Fructose-bisphosphate aldolase A Muscle-type antibody GSD12 antibody HEL S 87p antibody Lung cancer antigen NY LU 1 antibody Lung cancer antigen NY-LU-1 antibody MGC10942 antibody MGC17716 antibody MGC17767 antibody Muscle type aldolase antibody Muscle-type aldolase antibody RNALDOG5 antibody
Application: WB,IHC-P,IF-Cell,IF-Tissue
Epitope Region: Synthetic peptide within N-terminal human Aldolase .
Protein Target: ALDOA, ALDA
Target Species: Human,Mouse,Rat,Zebrafish
Species Reactivity: Human,Mouse,Rat,Zebrafish