mouse monoclonal IgG1; γB-crystallin Antibody (D-5) is an IgG1 κ mouse monoclonal gamma B-crystallin antibody (also designated γB-crystallin antibody) that detects the gamma B-crystallin protein of mouse, rat and human origin by WB, IP, IF and ELISA. γB-crystallin Antibody (D-5) is available as both the non-conjugated anti-gamma B-crystallin antibody form, as well as multiple conjugated forms of anti-gamma B-crystallin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Crystallins, the major proteins of the vertebrate eye lens, are responsible for maintaining the transparency and the refractive index of the lens. Crystallins are divided into α, β, and γ families, all of which usually contain seven distinctive protein regions, including four homologous motifs, one connecting peptide and N- and C-terminal extensions. The γ-crystallin family is comprised of seven closely related proteins designated γA-, γB-, γC-, γD-, γE-, γF- and γG-crystallin. γB-crystallin, also known as CRYGB or CRYG2, is a 175 amino acid member of the γ-crystallin family. Functioning as a monomer that has a two-domain beta fold, γB-crystallin, like other members of its family, plays a key role in ensuring the proper structure of the vertebrate eye lens. Defects in the gene encoding γB-crystallin are associated with the formation of cataracts which are characterized by a clouding of the crystalline lens of the eye.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.