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Human Ryanodine Receptor 1, RYR1 ELISA Kit

Bioassay Technology Laboratory


Calcium Channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules (PubMed: 11741831, PubMed: 16163667). Repeated very high-level exercise increases the open probability of the Channel and leads to Ca(2+) leaking into the cytoplasm (PubMed: 18268335). Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity).


  • GeneID: 6261
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 565,176
  • Synonyms: Ryanodine receptor 1;RYR 1;RYR1;RYR-1;Skeletal muscle calcium release Channel;Skeletal muscle ryanodine receptor;Skeletal muscle-type ryanodine receptor;Type 1 ryanodine receptor
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: RYR1
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 0.05ng/ml
  • Target Protein: RYR1
  • Detection Range: 0.1-30ng/ml
  • Full Product Name: Ryanodine Receptor 1
  • Standard Solution: 32ng/ml
  • UniProt Accession: P21817