RC219-19
human Osteoprotegerin (OPG), 10ug
Bio Basic
DESCRIPTION
OPG, Osteoprotegerin, human: Osteoprotegerin (OPG) is a member of the TNFR superfamily that can act as a decoy receptor for RANKL. Binding of soluble OPG to sRANKL inhibits osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, thereby leading to excess accumulation of bone and cartilage. OPG is expressed in a wide variety of tissues including adult heart, lung, kidney, liver, spleen, prostate, lymph node and bone marrow. OPG is secreted both as a monomeric and a dimeric protein. Its primary structure consists of seven distinct domains, four of which corresponds to the extracellular cysteine-rich domains of TNFR proteins and constitutes the soluble OPG. UnitProt ID: O00300
DETAILS
- Unspsc Code: 12352202
- Bbi Code Sku: RC219-19.SIZE.10ug
- Unspsc Category: Other Proteins
- Storage Conditions: (-15 to -20)C
- Tags Search Keywords: Recombinant Proteins human Osteoprotegerin (OPG), 10ug
- Product Category Level 1: Proteins
- Product Category Level 2: Recombinant Proteins
- Product Category Level 3: Other
- Shipping Conditions Rtice: ICE
- Refrigeration Requirements: Freezer