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Animal-Free Recombinant Human IL-17E



IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulates secretion of IL-8, and induces activation of the transcription factor NF-kappaB in cells that express the IL-17BR receptor. Recombinant Human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 146 amino acid polypeptide chains.


  • Gene Id: 64806
  • Uniprot: Q9H293
  • Activity: Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100 ng.
  • Category: RUO Cytokines
  • Subcategory: Animal-Free Cytokines
  • Research Areas: Cancer, Immune System, Inflammation, COVID-19
  • Alternative Names: Interleukin-17E, IL-25
  • Species of Origin: Human
  • Expression System Source: E.coli