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12-1022-20 12-1022

Recombinant Rabbit Monoclonal Antibody to CD15 / FUT4 (Reed-Sternberg Cell Marker)(Clone : FUT4/1478R)

Abeomics

DESCRIPTION

CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

DETAILS

  • Gene: FUT4
  • App Id: FACS,IF,IHC
  • Antigen: CD15 / FUT4 (Reed-Sternberg Cell Marker)
  • Gene Id: 2526
  • Isotype: Rabbit IgG
  • Format Id: Purified
  • Clone Name: FUT4/1478R
  • Uniprot Id: P22083
  • Clonality Id: Monoclonal
  • Purification: Purified Ab with BSA and Azide at 200ug/ml
  • Reactivity Id: Human, Mouse, Rat
  • Product Content: 200ug/ml of Ab purified by Protein A Column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & Azide at 1.0mg/ml.
  • Alternative Name: 3 Fucosyl N Acetyl Lactosamine, Alpha (1,3) Fucosyltransferase, Alpha 13 fucosyltransferase FucT, ELAM Ligand Fucosyltransferase, ELFT, FCT3A, Fuc-TIV, Fucosyltransferase 4 Alpha 1 3 Fucosyltransferase Myeloid Specific, Fucosyltransferase 4, Galactoside 3 L Fucosyltransferase, Lewis X.
  • Application Note: Flow Cytometry (1-2µg/million cells); Immunofluorescence (1-2µg/ml); Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 8.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes)
  • Storage Condition: Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
  • Immunogen Information: Purified human neutrophils