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HY-138697A

S65487 (sulfate)

MedChem Express

- Open Babel Depiction N O N H 3 C CH 3 HO N N CH 3 N O Cl H 3 C O N

DESCRIPTION

S65487 (VOB560) sulfate, a potent and selective Bcl-2 inhibitor, is a proagent of S55746. S65487 sulfate is also active on BCL-2 mutations, such as G101V and D103Y. S65487 sulfate has poor affinity with MCL-1, BFL-1 and BCL-XL. S65487 sulfate induces apoptosis and has anticaner activities[1][2].

DETAILS

  • Purity: >98%
  • Smiles: O=C(C1=C(C)N(C)C(C2=C(C=CC(Cl)=C2)C(N3[C@@H](CC4=CC=CC=C4C3)CN5CCOCC5)=O)=C1)N(C6=CC=C(C=C6)O)C7=C(C)N(C)C(C#N)=C7.O=S(O)(O)=O
  • Category: Reference compound
  • Lead Time: 1-2 days
  • Cas Number: 2416937-01-2
  • Molecular Weight: 815.33
  • Molecular Formula: C41H43ClN6O8S

Lead Time: 1-2 days

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