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11758

Tetrahydropiperine

Cayman Chemical

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DETAILS

  • Inchi: InChI=1S/C17H23NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h8-9,12H,1-7,10-11,13H2
  • Purity: ≥95%
  • Raptas: Product Type|Biochemicals|Ion Channel Modulation||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Product Type|Biochemicals|Small Molecule Inhibitors|Demethylases||Research Area|Toxicology & Xenobiotic Metabolism|Cytochrome P450s|CYP1A1
  • Smiles: O=C(CCCCC1=CC(OCO2)=C2C=C1)N3CCCCC3
  • Inchikey: APZYKUZPJCQGPP-UHFFFAOYSA-N
  • Cas Number: 23434-88-0
  • Formulation: A solution in ethanol
  • Storage Temp: -20
  • Shipping Temp: -20
  • Formula Markup: C17H23NO3
  • Formula Weight: 289.4
  • Shelf Life Days: 730

DESCRIPTION

A derivative of piperine; a TRPV1 agonist (EC50 = 6.3 µM); inhibits rat hepatic microsomal AHH (IC50 = 23 µM) and MOCD activity in rat liver microsomes (IC50 = 25 µM); increases skin pigmentation in a mouse model of vitiligo when 100 µl of a 175 mM solution is administered topically