T70428
Nepaprazole sodium
TargetMol
DESCRIPTION
Nepaprazole Na is the salt form of Nepaprazole Free Base, also known as TY-11345, is a proton pump inhibitor potentially for treatment of gastric ulcer. TY-11345 potently inhibited H+/K(+)-ATPase activity in isolated rabbit gastric mucosal microsomes; and the inhibitory effect was enhanced under weak acid conditions, the IC50 (concentrations that inhibit the enzyme activity by 50%) being 5.8 microM and 9.9 microM at pH 6.0 and pH 7.4, respectively. TY-11345 should be useful for the clinical treatment of peptic ulcer diseases.
DETAILS
- Cas: 157564-11-9
- Purity: 98%
- Smiles: [Na+].[H][C@]1(CCCCc2c(OC)ccnc12)S(=O)c1nc2ccccc2[n-]1
- Category: Compound
- Molecular Weight: 363.41
- Molecular Formula: C18H18N3NaO2S
Lead Time: 4 - 5 weeks
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