Cynomolgus IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, His Tag&Twin-Strep Tag (MALS verified)

DESCRIPTION

Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

DETAILS

Tag: C-10×His | C-Twin-Strep
Host: HEK293
Size: 1mg
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Cynomolgus IL-2RB&IL-2RA&IL-2RG Protein, His Tag&Twin-Strep Tag (ILG-C52W3) is expressed from human 293 cells (HEK293). It contains AA Glu 22 - Glu 213 & Leu 23 - Pro 255 (Accession # Q38J85-1 & H6WS54 & Q38JL2-1).
Storage: -20℃
Category: Bio-Markers & CD Antigens
Molecule: IL-2 R beta & IL-2 R alpha & IL-2 R gamma
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Glu 22 - Glu 213 & Leu 23 - Pro 255
Swiss-prot: Q38J85-1 & H6WS54 & Q38JL2-1
Package Size: 500ug*2
Characteristics: Cynomolgus IL-2RB&IL-2RA&IL-2RG, His Tag&Twin-Strep Tag is produced by co-expression of IL-2RB and IL-2RA and IL-2RG, has a calculated MW of 30.1 kDa (IL-2RB) and 55.9 kDa (IL-2RA&IL-2RG). Subunit IL-2RB is fused with a his tag at the C-terminus and subunit IL-2RA&IL-2RG is fused with a Twin-Strep Tag at the C-terminus. The reducing (R) protein migrates as 37-44 kDa and 85-100 kDa respectively due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 30.1 kDa | 55.9 kDa
Shipping Condition: RT
Species Reactivity: Cynomolgus
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