Cav1.3 Antibody, Clone S48: APC

DESCRIPTION:

Mouse Anti-Rat Cav1.3 Monoclonal IgG2a Kappa

DETAILS

Target: Cav1.3
Gene Id: 29716
Isotype: IgG2a Kappa
Conjugate: APC
Immunogen: Fusion protein amino acids 859-875 of rat Cav1.3
References: 1. Zhang Z., et al. (2005) Circulation 112: 1936-1944. 2. Johnson S.L. and Marcotti W. (2008) The Journal of Physiology. 586: 1029-1042.
Swiss Prot: P27732
Specificity: Detects ~250kDa. No cross-reactivity against Cav1.2.
Applications: WB | IHC | ICC/IF | IP | AM
Clone Number: S48
Field Of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Host Species: Mouse
Product Type: Monoclonal
Purification: Protein G Purified
Concentration: 1 mg/ml
Research Areas: Neuroscience | Ion Channels | Calcium Channels | Voltage-Gated Calcium Channels | Cancer | Cell Signaling
Storage Buffer: PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Accession Number: NP_058994.1
Alternative Names: alpha-1 polypeptide Antibody, CAC1D_HUMAN Antibody, CACH3 Antibody, CACN4 Antibody, CACNA 1D Antibody, Cacna1d Antibody, CACNL1A2 Antibody, Calcium channel Antibody, Calcium channel L type alpha 1 polypeptide isoform 2 Antibody, Calcium channel neuroendocrine/brain type alpha 1 subunit Antibody, Calcium channel voltage dependent L type alpha 1D subunit Antibody, CCHL1A2 Antibody, isoform 2 Antibody, L type Antibody, Voltage dependent L type calcium channel subunit alpha 1D Antibody, Voltage gated calcium channel alpha 1 subunit Antibody, Voltage gated calcium channel alpha subunit Cav1.3 Antibody, Voltage gated calcium channel subunit alpha Cav1.3 Antibody, Voltage-dependent L-type calcium channel subunit alpha-1D Antibody, Voltage-gated calcium channel subunit alpha Cav1.3 Antibody
Antibody Dilution: WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Cite This Product: StressMarq Biosciences Cat# SMC-301D-APC, RRID: AB_2700032
Immunogen Species: Rat
Storage Temperature: Conjugated antibodies should be stored according to the product label
Shipping Temperature: Blue Ice or 4ºC
Cellular Localization: Membrane | Cell Membrane
Scientific Background: CaV1.3, also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), is a human gene. CaV1.3 subunits are primarily expressed in neurons and neuroendocine cells. Some studies suggest however that CaV1.3 is also found in the atria, and may figure prominently in atrial arrhythmias (1). CaV1.3 also carries the primary sensory receptors of the mammalian cochlea, and are also expressed in the electromotile outer hair cells (2).
Certificate Of Analysis: 1 µg/ml of SMC-301 was sufficient for detection of Cav1.3 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Species Reactivity Full Name: Human | Mouse | Rat