Human IL-35 R / gp130 & IL12Rb2 Protein, His Tag (MALS verified)

DESCRIPTION

Interleukin 35 (IL-35) is a recently discovered anti-inflammatory cytokine from the IL-12 family. Member of IL-12 family - IL-35 is produced by wide range of regulatory lymphocytes and plays a role in immune suppression. IL-35 can block the development of Th1 and Th17 cells by limiting early T cell proliferation. The heterodimeric cytokine of IL-35 involves two subunits of p35 and Ebi3 which are also seen in IL-12 and IL-27. IL-35 is recognized as a defi nite immunosuppressor with a huge potent of suppression.

DETAILS

Tag: C-10×His | Native
Host: HEK293
Size: 50ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 95%
Source: Human IL-35 R, His Tag (ILR-H52H8) is expressed from human 293 cells (HEK293). It contains AA Glu 23 - Glu 619 & Lys 24 - Asn 622 (Accession # P40189-1(gp130) & Q99665-1(IL12Rb2)).
Storage: -20℃
Category: Cytokines&Growth Factors
Molecule: IL-35 R
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Glu 23 - Glu 619 & Lys 24 - Asn 622
Swiss-prot: P40189-1(gp130) & Q99665-1(IL12Rb2)
Package Size: 50ug*1
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 73.1 kDa & 71.5 kDa. The protein migrates as 95-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 73.1 kDa & 71.5 kDa
Shipping Condition: RT
Species Reactivity: Human
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