mouse monoclonal IgG2a; SgK269 Antibody (EB-8) is an IgG2a κ mouse monoclonal SgK269 antibody (also designated SgK269 antibody) that detects the SgK269 protein of human origin by WB, IP and ELISA. SgK269 Antibody (EB-8) is available as the non-conjugated anti-SgK269 antibody. The critical involvement of protein tyrosine kinases in signal transduction pathways is well established. These kinases can be divided into two major groups, including the receptor tyrosine kinases and the non-receptor type kinases. Non-receptor type kinases, such as Src kinases, are generally associated with the internal portion of the plasma membrane and may function as signal transducers in association with surface receptors that lack an intracellular catalytic domain. The receptor tyrosine kinase group is comprised of more than 50 members, belonging to 14 families. Ligand-induced tyrosine phosphorylation of such receptors induces receptor dimerization and subsequent autophosphorylation of specific individual phosphotyrosine residues located within their cytoplasmic domains, which serve as binding sites that interact with specific cytoplasmic molecules. SgK269 (sugen kinase 269), also known as NKF3 kinase family member, is a 1,746 amino acid protein that belongs to the protein kinase superfamily. SgK269 contains one protein kinase domain and is believed to function as a protein tyrosine kinase.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.