RP00977
Recombinant Human IFN-lambda 1/IL-29 Protein
ABclonal
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DESCRIPTION
This protein is also known as cytokine Zcyto21, Interferon lambda-1, IFN-lambda-1, and IFNL1, is a secreted protein which belongs to the IL-28 / IL-29 family. IL-29 is a cytokine with immunomodulatory activity. IL-29 is highly similar in amino acid sequence to the IL-28. IL-28 and IL-29 are induced by viral infection and showed antiviral activity. IL-28 and IL-29 interacted with a heterodimeric class II cytokine receptor that consisted of IL-1 receptor beta (IL-1Rbeta) and an orphan class II receptor chain, designated IL-28Ralpha. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II cytokine receptor composed of IL1RB and IL28RA. The ligand / receptor complex seems to signal through the Jak-STAT pathway.
DETAILS
- Tag: C-His
- Source: HEK293 cells
- Gene Id: 282618
- Species: Human
- Lead Time: 3-5 weekdays
- Swiss Prot: Q8IU54
- Research Areas: Interleukin,Cytokines & Cytokine receptors
- Alternative Names: IFNL1,IL-29,IL29
Equivalent Items
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