DESCRIPTION

• Tag: C-10×His & C-Avi
• Host: HEK293
• Size: 25ug
• Buffer: PBS, pH7.4
• Format: Powder
• Purity: 95%
• Storage: -20℃
• Category: MABSol® Biotin Labeled Proteins
• Molecule: Spike RBD
• Accession: QHD43416.1 (Y449H, E484K, N501Y)
• Conjugate: Biotin-labeled
• Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
• Exp Region: Arg 319 - Lys 537
• Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 28.2 kDa. The protein migrates as 32-38 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin Level: 1.0 EU per μg
• Molecular Weight: 28.2 kDa
• Shipping Condition: RT
• Species Reactivity: SARS-CoV-2
• Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html