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1596589-50mg 1596589-10mg

Nelfinavir mesylate

Biogems

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DESCRIPTION

Nelfinavir is a potent competitive inhibitor of the HIV-1 protease. It is reported that it can also inhibit the growth of various cell types and trigger apoptosis.

DETAILS

  • Purity: ≥98%
  • Synonyms: AG-1343, AG1343, Viracept
  • Cas Number: 159989-65-8
  • References: Kaldor, S. W., Kalish, V. J., Davies, J. F., Shetty, B. V., Fritz, J. E., Appelt, K., ... & Dressman, B. A. (1997). Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease. Journal of medicinal chemistry, 40(24), 3979-3985. Dube, M. P., Parker, R. A., Tebas, P., Grinspoon, S. K., Zackin, R. A., Robbins, G. K., ... & Snyder, S. W. (2005). Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides. Aids, 19(16), 1807-1818. Gills, J. J., LoPiccolo, J., & Dennis, P. A. (2008). Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy.Autophagy, 4(1), 107-109.
  • Application: FA
  • Formulation: Crystalline solid
  • Chemical Name: (3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylsulfanylbutyl]-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinoline-3-carboxamide;methanesulfonic acid
  • Molecular Weight: 663.9
  • Molecular Formula: C32H45N3O4S CH3SO3H
  • Storage Conditions: Product should be kept at -20°C.
  • Pubchem Openeye Can Smiles: CC1=C(C=CC=C1O)C(=O)NC(CSC2=CC=CC=C2)C(CN3CC4CCCCC4CC3C(=O)NC(C)(C)C)O.CS(=O)(=O)O