Z02751-10
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BMP-7, Human
GenScript
DESCRIPTION
Human BMP-7 is one of at least 15 structurally and functionally related BMPs, which are members of the transforming growth factor β (TGF-β) superfamily. BMPs were originally identified as protein regulators of cartilage and bone formation. However, they havesince been shown to be involved in embryogenesis and morphogenesis of various tissues and organs. BMPs have also been shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. BMP-7 is synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.
DETAILS
- Form: Lyophilized
- Purity: > 95% as analyzed by SDS-PAGE> 95% as analyzed by HPLC
- Species: Human
- Applications: 1. Molecular standard (Western, ELISA) in studying secreted BMP-7;2. Preparing antibodies for BMP-7 monomer;3. Molecule standard in detecting secreted BMP-7 in reduced SDS-PAGE.
- Product Line: Cytokines
- Expression System: E. coli
- Storage Stability: Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.
- Protein Construction: BMP-7 (Ser293-His431)\nAccession # P18075