71321-1 71321-2
PD-L1 (D122A), Fc fusion, Biotin-labeled (Human) HiP™ Recombinant
BPS Bioscience
DESCRIPTION
Human secreted Programmed
Cell Death 1 Ligand 1 (PD-L1)-Fc fusion
protein, also known as CD274 and B7
homolog 1 (B7-H1) with a D122A mutation,
GenBank Accession No. NM_014143,
amino acids 19-239, fused at the Cterminus
with the Fc portion of human IgG1,
with C-terminal Avi-tag™ expressed in a
HEK293 cell expression system and
enzymatically biotin-labeled using Avi-tag™
technology. MW = 54 kDa.
DETAILS
- Aa: 19-239
- Mw: 54 kDa
- Tags: C-terminal Fc fusion (Human IgG1), C-terminal Avi-tag™
- Format: Aqueous buffer solution
- Genbank: NM_014143
- Species: Human
- Uniprot: Q9NZQ7
- Shiptemp: -80°C (dry ice)
- Synonyms: Programmed Cell Death 1 Ligand 1, PDL1, PD-L1, B7 homolog 1, B7H1, B7-H1, CD274, PDCD1L1
- Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
- Category: Immunotherapy/Protein
- References: 1. Freeman, G.J., et al. J. Exp. Med. 2000; 192(7): 1027-1034 2. Dong, H., et al., Nat. Med. 1999; 5(12): 1365-1369.
- Description: Human secreted Programmed Cell Death 1 Ligand 1 (PD-L1)-Fc fusion protein, also known as CD274 and B7 homolog 1 (B7-H1) with a D122A mutation, GenBank Accession No. NM_014143, amino acids 19-239, fused at the Cterminus with the Fc portion of human IgG1, with C-terminal Avi-tag™ expressed in a HEK293 cell expression system and enzymatically biotin-labeled using Avi-tag™ technology. MW = 54 kDa.
- Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
- Unspsc Code: 12352202
- Unspsc Name: Proteins
- Applications: Useful for the study of protein-protein interaction, epitope mapping, and in vitro and in vivo protein function.
- Product Type: Protein
- Biosafety Level: Not applicable (BSL-1)
- Related Products: 71105-2, 71213, 72016, 79572, 79512
- Storage Stability: At least 6 months at -80°C.
- Scientific Category: Immunotherapy