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E4851Hu

Human Potassium Voltage-gated Channel Subfamily E Member 1, KCNE1 ELISA Kit

Bioassay Technology Laboratory

DESCRIPTION

Ancillary protein that assembles as a beta subunit with a voltage-gated potassium Channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the Channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium Channel KCNB1 (PubMed: 19219384). Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) Channel. The outward current reaches its steady state only after 50 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).

DETAILS

  • GeneID: 3753
  • Species: Human
  • Storage: 2-8ºC
  • MASS(Da): 14,675
  • Synonyms: Delayed rectifier potassium Channel subunit IsK;IKs producing slow voltage-gated potassium Channel subunit beta Mink;KCNE 1;KCNE1;Minimal potassium Channel;Potassium voltage-gated Channel subfamily E member 1
  • Assay Time: 1h 30m
  • Assay Type: Sandwich
  • Gene Names: KCNE1
  • Reactivity: Human
  • Sample Type: Serum, plasma, cell culture supernates
  • Sensitivity: 10.55ng/L
  • Target Protein: KCNE1
  • Detection Range: 20-3500ng/L
  • Full Product Name: Potassium Voltage-Gated Channel Subfamily E Member 1
  • Standard Solution: 4000ng/L
  • UniProt Accession: P15382