1125931-10g 1125931-1g
Gatifloxacin
Biogems
DETAILS
- Purity: ≥98%
- Synonyms: AM-1155, gatifloxacine, Tequin, Zymar
- Cas Number: 112811-59-3
- References: Perry, C. M., Balfour, J. A. B., & Lamb, H. M. (1999). Gatifloxacin. Drugs,58(4), 683-696. Fung-Tomc, J., Minassian, B., Kolek, B., Washo, T., Huczko, E., & Bonner, D. (2000). In vitro antibacterial spectrum of a new broad-spectrum 8-methoxy fluoroquinolone, gatifloxacin. Journal of Antimicrobial Chemotherapy, 45(4), 437-446. Desbordes, S. C., Placantonakis, D. G., Ciro, A., Socci, N. D., Lee, G., Djaballah, H., & Studer, L. (2008). High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell stem cell, 2(6), 602-612.
- Application: FA
- Formulation: Crystalline solid
- Chemical Name: 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
- Molecular Weight: 375.4
- Molecular Formula: C19H22FN3O4
- Storage Conditions: Product should be kept at -20°C.
- Pubchem Openeye Can Smiles: CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
DESCRIPTION
Gatifloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV. It is potent against gram positive and gram negative bacteria and is reported to promote self-renewal in cultured embryonic stem cells.