Salubrinal

DESCRIPTION

A selective phosphatase inhibitor which prevents dephosphorylation of eIF2α, protecting cells from ER stress-mediated apoptosis (EC50 = 15 μM); prevents replication of herpes virus (IC50 = 3 μM) and alters bone formation

DETAILS

Inchi: InChI=1S/C21H17Cl3N4OS/c22-21(23,24)19(27-17(29)12-11-14-6-2-1-3-7-14)28-20(30)26-16-10-4-8-15-9-5-13-25-18(15)16/h1-13,19H,(H,27,29)(H2,26,28,30)/b12-11+
Purity: ≥95%
Raptas: Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Small Molecule Inhibitors|Phosphatases||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Infectious Disease|Viral Diseases|HSV
Smiles: O=C(NC(NC(NC1=C(N=CC=C2)C2=CC=C1)=S)C(Cl)(Cl)Cl)/C=C/C3=CC=CC=C3
Inchikey: LCOIAYJMPKXARU-VAWYXSNFSA-N
Cas Number: 405060-95-9
Formulation: A crystalline solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C21H17Cl3N4OS
Formula Weight: 479.8
Shelf Life Days: 1460