Pulmospheres-Derived Mini-Lungs
Use a 3D lung model derived from patients’ multicellular spheroids to understand the dynamics of Idiopathic Pulmonary Fibrosis (IPF) medications on the disease.
Lung systems (3D pulmospheres) could serve as a personalized and predictive multicellular model for the assessment of antifibrotic drugs. QMCF technology is a stable episomal expression system that uses specific mammalian cells and appropriate vectors for production of secretable and intracellular recombinant proteins, antibodies and virus-like particles as well as for expression of intracellular proteins at a physiologically relevant level for the development of cell-based assays for screening purposes. Source
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