Simplicon RNA Reprogramming Technology
Generate high numbers of human iPSCs with a single transfection step utilizing a single, polycistronic, synthetic, self-replicating RNA strand.
The Simplicon™ RNA reprogramming technology does not rely on lentiviral, retroviral or RNA-based viruses and is a step toward a more defined system for iPS cell generation. This RNA-based reprogramming approach has broad applicability for the efficient generation of hiPSCs for use in disease cell-modeling studies, transdifferentiation studies and eventual human cell therapy/regenerative medicine applications. Source
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