Use a transgenic C. elegans larva humanized with disease-related genes in a liquid format for the fast and easy assessment of transgene activity.
RediMODEL is a novel way to determine if mutations in important genes cause disease. Using humanized C. elegans as a model system, individual human mutations are inserted into the animal model genome; the humanized animal model with clinical variant installed is then screened with simple protocols for its effects on normal gene function. Source