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Cytotoxicity

Test for effects on cell viability and proliferation
Cell Proliferation

Measure cell number, cell viability and cell division.
Cell Viability

Measure changes in cell number, cell division, DNA content or a cell metabolism marker such as ATP levels.
Cytotoxicity Testing

Determine whether a cosmetic product or ingredient is toxic to in vitro cell cultures.
In Vitro Skin Models

Measure skin model penetration and invasion, photosensitivity and toxicity.
Skin Permeability

Use human skin models to determine transdermal delivery and percutaneous absorption of pre-clinical drugs.
OECD 471: Bacterial Reverse Mutation Test (Ames)

Measure the mutagenic potential of test compounds.
Nuclear Receptor Assays

Measure nuclear receptor activity in biochemical and cell assays.
OECD 487: In Vitro Mammalian Cell Micronucleus Test

Assess whether a test substance induces chromosomal changes in cultured cells.
OECD 474: Mammalian Erythrocyte Micronucleus Test

The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone marrow and/or peripheral blood cells of animals, usually rodents (mice or rats).
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