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Predictive Biomarkers Discovery

Identify candidate biomarkers suggestive of a response to a treatment.
3D Cell Culture

Use a scaffold-based or scaffold-free format to grow three dimensional cell and tissue structures.
Pharmacodynamic Biomarkers Discovery

Identify candidate biomarkers indicative of the therapeutic outcome of a drug-target interaction.
Human Primary Cells

Acquire fresh/frozen human primary cells based on patient demographics, disease stage, history and treatment. Cell Lines typically refer to legacy immortalised cells, that can be cultured and passaged “indefinitely” Primary Cells are cells that have been isolated from fresh tissue (or cultures) that have not be immortalised and after a certain amount of passaging they will reach senescence. iPSCs, induced pluripotent stem cells, are cells that have (through GM or culturing conditions) have been revert back to the pluripotency state. The original cells can be a cell line or a primary cell.
Model Development

Develop a disease model.
Organotypic Culture

Co-culture different cells to enable in vitro growth of an in vivo tissue or organ equivalent.
Human Organs-On-Chips

Use Organs-On-Chips for target identification and validation, target-based screening, and phenotypic screening.
Human Organoids

Test immuno-oncology drugs and therapies on fresh, unpropagated 3D tumor organoids to evaluate efficacy and understand drug mechanism of action. Understand the intact tumor immune microenvironment, cytotoxic efficacy and tumor-drug interaction.
Human 3D cultures

Provision of 3D culture of Human Primary Cells