The Bioinformatics and Biostatistics Core provides efficient, high quality computational and statistical expertise for Van Andel Research Institute laboratories and external organizations in the analysis and interpretation of data.

The core maintains sequencing pipelines for processing and analyzing genomic data sets, develops custom tools and applications for quantitative image analysis, provides access to a variety of proprietary and open-source resources, and oversees the maintenance and development of high-performance computing capabilities. Services include:

• Statistical consulting
• Experimental design
  • Research proposal development
  • Sample size determination
  • Randomization procedures
• Manuscript preparation and data deposition
• Genomic variant detection and annotation
• Transcript/isoform differential expression
• DNA copy number determination
• Systems-level analysis such as gene-set and network-based analysis
• Analysis, interpretation, and presentation of small and large data sets
  • Time-series data
  • Tumor growth
  • Drug response
• Custom application and tool development