Our Mission
The RPPA Core provides investigators with a powerful, high‐throughput, quantitative, cost‐effective technology for functional proteomics studies. Furthermore, we provide centralized, standardized and quality-controlled services to investigators not only throughout MD Anderson, but around the world, as well as to several national consortia, including TCGA, CCLE and ICBP.
Our Method
RPPA represents an antibody‐based functional proteomic analysis for both tumor tissue and cultured cells. RPPA characterizes the basal protein expression and modification levels, growth factor‐ or ligand‐induced effects, and time‐resolved responses appropriate for systems biology analysis. It provides information to integrate the consequence of genetic aberrations in cancer, to validate therapeutic targets, to demonstrate on‐ and off‐target activity of drugs, and to evaluate drug pharmacodynamics.
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UT MD Anderson Cancer Center Reverse Phase Protein Array (RPPA) Core
6565 MD Anderson Boulevard
Houston, TX, 77030
United States
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UT MD Anderson Cancer Center Reverse Phase Protein Array (RPPA) Core
6565 MD Anderson Blvd. Room Z4.2040
Houston, , TX , 77030
United States
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