The High Resolution Electron Microscopy Facility (HREMF) provides a resource to the scientific community at MD Anderson for high resolution imaging of cells, tissues, organs or polymers containing cancer agents. The facility is located at the Smith Research Building (South Campus) and houses a JEOL JEM-1010 transmission electron microscope (TEM), a JEOL JSM-5900 scanning electron microscope (SEM) equipped with a backscattered electron detector, a Bal-Tec Technotrade coating system, a Leica Ultramicrotome, Leica Ultrostainer and other ancillary accessories needed to prepare samples for SEM and TEM. A technologist with histological training is available to assist researchers in defining their specific needs related to SEM and TEM. Both electron microscopes are equipped with digital cameras. The facility operates on a charge-back basis only for processing of samples and the number of microscope hours used to examine samples with technical assistance.