The mission of the Tissue Procurement Facility (TPF) is to serve as a centralized resource for standardized patient consent, sample collection, processing, storage, quality control, distribution, and electronic record maintenance. Since the 1996 inception of the TPF, over 80,000 tissue samples including well-preserved samples of malignant and benign tumors, organ-matched normal tissue, and other types of diseased tissues, have been collected from surgical specimens obtained at the University of Minnesota Medical Center-Fairview (UMMC-F) University Campus. Approximately one-third of these specimens have been distributed to researchers, the remaining ~two-thirds are available for research, and ~5300 new specimens are obtained annually.