OResearch in the Department of Bioengineering and Therapeutic Sciences ranges from the foundational to the translational, from discoveries about the structures and functions of molecules and sub-cellular structures underlying health and disease to the development of microdevices and modified cells to precisely deliver drugs or even provide implantable bioartificial replacement organs.

Hallmarks of department research include the development of personalized, precision medicine by revealing genetic differences underlying disease prevalence, severity, and drug response. Techniques developed here identify and detect biomarkers of disease sub-types, progression, and treatment response, from tissue imaging to genetic testing and individual cell analysis, that aid the more rapid development of new treatments and guide their clinical applications.

Department scientists use computational modeling, bioinformatics, and quantitative pharmacology to integrate data from diverse experimental and clinical sources to discover new drugs and drug targets, as well as to design more efficient and informative preclinical and clinical safety and efficacy studies.