Tioga Research provides CRO services, focusing on the research and early development of skin-applied products. We take on projects from product concept assessment through to IND, or for one or more stages in between. We have particular strengths in formulations innovation and skin delivery screening. If you seek to assess, devise, create or develop an innovative topical or transdermal drug product, we might well be able to help.

We deliver services from concept to IND:
• Analytical method development & verification
• Preformulation (solubilities, compatibilities etc.)
• Formulation reverse engineering & replication
• Formulation innovation (for optimal performance & patentability)
• Skin absorption screening (Franz diffusion cells & proprietary platforms)
• High throughput experimentation platform engineering & deployment
• in vitro release testing (“IVRT”) & in vitro permeation testing (“IVPT”)
• Formulation optimization
• Stability
• Esthetics panels
• Skin safety studies (employing third-party CRO)
• IVRT & IVPT under GLP conditions
• Technology transfer to GMP facility
• Patent application support