Our SPA™ technology enables rapid and accurate solubility screening from less than 100 µg of solid material from anonymous samples! The Solubility Company is a trusted preclinical CRO providing physicochemical measurement services based on the proprietary SPA method. Our Clients come to us when kinetic solubility data is not enough. Our SPA™ technology enables rapid and accurate solubility screening from less than 100 µg of solid material from anonymous samples!

Through the innovative combination of optics, fluidics, automation and intelligent digital pattern recognition algorithms, the SPA method measures the thermodynamic, apparent solubility and related physicochemical parameters of practically any solid sample, with a turnaround of 24h from receipt of sample.

Our service laboratory is based in Helsinki, Finland and is operated by a highly skilled team with more than 50 years of experience in pharmaceutical development, high-tech R&D and management.

We offer a range of physicochemical measurement services based on the proprietary SPA method:
-solubility
-thermodynamic/apparent/intrinsic/native solubility
- dissolution rate
-IDR
- pKa
- logP and logD
in buffer solutions, physiological solutions and organic solvents.