The mission of the Bioinformatics Knowledge Unit (BKU) is to empower life sciences researchers at the Technion and its affiliated hospitals by using computational methods and tools to make their research more productive, saving time, effort and cost. The BKU’s responsibilities are to provide consulting to individual laboratories, arrange workshops and seminars for students, technical, and academic staff, and make state-of-the-art computing tools, data resources, and computing power available to all. The consulting activities include helpdesk services as well as on-going involvement in research projects and grants. Other modes of cooperation are possible, ideas and suggestions are welcome.