CEED is recognized for its mechanistic studies defining the role of environmental exposures in disease pathogenesis. The Core works closely with other Research Cores to incorporate biological response indicators or biomarkers into clinical and population studies to mitigate exposures and disease. By engaging the Community Outreach and Education Core, this Core is able to translate findings to vulnerable populations, diseased cohorts, and interested stakeholders. Using model systems, human studies, and emerging science and technologies to identify vulnerable populations and developmental stages, they study uptake and metabolism as a function of genetic and epigenetic background and life stage, and develops biological response indicators that link exposures to disease.
The Core has four mechanistic themes that cut across disease endpoints:
Influence of age and development on toxicity
Transport and metabolism of toxicants
Cellular injury; inflammation, and repair
Epigenetic and genetic mechanisms in toxicity and pathogenesis
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Rutgers University EOHSI NIEHS CEED Environmental/Chemical Pathogenesis
170 Frelinghuysen Road, Room 414
Piscataway, , NJ , 08854
United States
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Rutgers University EOHSI NIEHS CEED Environmental/Chemical Pathogenesis
170 Frelinghuysen Road
Piscataway Township, NJ, 08854
United States
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