The Histopathology Shared Resource provides high quality, cost effective histopathology services and capitalizes on limited tissue resources to provide The Cancer Institute of New Jersey members with large collections (tissue microarrays) of human or animal, normal or tumor histology specimens to identify and/or quantify the expression of proteins, mRNAs, and the presence of whole chromosomes as well as individual genes. State-of-the-art imaging technology is available for Cancer Institute members to analyze and archive their histologic specimens.

The specific objectives of this shared resource are:

To provide immunohistochemical localization of cells and antigens using well-characterized antibodies in normal and malignant tissues
To define optimal conditions for novel, investigator-developed antibodies to localize tissue antigens
To provide tissue sections for investigators to procure pure cells from specific microscopic regions of tissue sections using microdissection
To assist investigators with all types of staining techniques (IHC, FISH, ISH, Q-dot) needed for visualization of cells/proteins including multi-color labeling
To construct TMA blocks for investigator-initiated translational research
To provide TMA sections containing large numbers of normal and malignant tissue cores
To work in conjunction with the Biomedical Informatics Shared Resource who provides state of the art imaging technology for analyzing and archiving histologic biospecimens.