The fermentation facility’s goal has been to provide affordable fermentation services to a highly diverse client base. Completely renovated in 2011 the fermentation facility, which meets BL2-LS containment requirements, is comprised of four contiguous operation units:
•Material Preparation Laboratory
•Fermentation In-Process
•Computer Control
•Product Recovery Room
Bio-reactor working capacities range from 10 to 800 liters. All systems are computer controlled with algorithm-based cascade-capable PID programming.
In the recovery room, downstream processing includes:
•Centrifugation
•Filtration
•Micro and Ultra-filtration
•Cell Disruption
With the advantage of having the world’s pharmaceutical industry in its backyard, a productive climate of industrial liaison has been the historical legacy of the facility. Many former facility students and graduates hold positions within the industry.
SERVICES:
Fermentation – Shake Flask to Bio-reactor volumes ranging from 1.5 to 800 liters.
Downstream Processing -
•Filtration
•Micro and Ultra-filtration
•Centrifugation
•Cell Distribution
•Extraction/Precipitation
Process Development/Optimization.
FEATURES/EQUIPMENT:
•Facility Containment Designation -BL2-LS.
•Process control via PID algorithm-based, cascade-capable, time and event based profiling.
•GEA Niro Soavi Pony series cell disruptor
•New Brunswick Scientific BioFlo PRO 1000 liter fermentors
•New Brunswick Scientific BioFlo 610 125 liter fermentors
•23 liter seed fermentors
•Virtis 20 SRC-X freeze dryer
•Sharples AS-26VB centrifuge