The Midwest Proteome Center is a new research resource facility at the Rosalind Franklin University of Medicine and Science, and comprises half of the Rosalind Franklin Structural Biology Laboratories. As a facility in support of biomedical research in proteomics, we serve the ongoing research endeavors on campus and the scientific community at-large by providing state-of-the-art modern technologies at a reasonable cost. The basic technologies employed include: protein separation, mass spectral analyses, protein identification, database mining and bioinformatics support. Protein and proteome analyses are particular focal points of the center.