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Taking SMA® one step further
Our goal is to inspire and assist you to push your application’s boundaries to the next level, utilizing styrene-maleic anhydride (SMA) copolymers and/or their derivatives. Besides offering commercial and experimental SMA-based copolymers for your research needs, we also aim to support your development efforts.

SMA®
Poly(styrene-maleic anhydride) copolymers (SMA®) are a highly versatile copolymer class, containing both hydrophobic moieties (styrene) and reactive, functionalizable moieties (anhydride).
The properties of the base polymer are determined by the ratio of styrene to maleic anhydride and by the molecular weight. SMA® native resins are amorphous thermoplastic polymers that are very transparent and exhibit high heat resistance and dimensional stability.

SMALP®
Styrene-maleic anhydride (SMA) copolymers are used as a detergent-free approach for membrane protein solubilization, isolation and cell membranes and subsequent characterization in downstream methods.
SMA copolymers have proven their value in the solubilization, purification, and characterization of a variety of membrane proteins, as described in over 200 scientific articles including comprehensive review articles. The usage of SMA copolymers for these applications is protected by patents for which Polyscope has liscences.