PolyAn GmbH – Molecular Surface Engineering for LifeScience consumables
PolyAn is a nanotechnology company specialized in the modification of surfaces using Molecular Surface Engineering (MSE). Since 1996 PolyAn develops and manufactures consumables for multiplex diagnostics and LifeScience research.

Microarray consumables
PolyAn is one of the leading producers of functionalized substrates for microarrays. We provide our customers with the broadest choice of surfaces, materials and designs on the market to help you choose the optimal consumable for your specific microarray. Our products include plastic and glass slides, coverslips as well as functionalized plastic films and 96-well microplates for DNA-, peptide-, glycan- or protein microarrays. With our microarray consumables we enable applications ranging from low density microarrays for diagnostic tests to ultra-high density arrays for pharma screening and academic research.

Fluorescent Microparticles (beads, microspheres) and nanoparticles
PolyAn is offering a portfolio of monodisperse microparticles (beads) for agglutination and turbimetric assays, cell interaction studies and instrument calibration. For flow cytometers and fluorescence imaging systems PolyAn offers multiplex bead sets with up to 25 distinct populations. PolyAn’s microparticles can be colour-encoded with a wide range of fluorescent dyes at the fluorescence intensity of your choice.

Using PolyAn’s Molecular Surface Engineering technology, the micro- and nanoparticles can be functionalized with different reactive 3D-matrices for covalent coupling of biomolecules: 3D-Carboxy for EDC/EDAC mediated coupling, 3D-Alkyne and 3D-Azide for „click chemistry“, Streptavidin and neutravidin for coupling of biotinylated biomolecules, 3D-Aldehyde for one-step coupling of biomolecules and Protein A/G for binding of IgG. A custom modification with antibodies or oligonucleotides is available upon request.

Functionalized Microplates for Immunoassays and PCR applications
Based on our Molecular Surface Engineering technology PolyAn is offering a range of reactive, functionalized microplates. These include both Amine-binding 3D-NHS functionctionalized plates, nucleophilic binding 3D-Epoxy plates, 3D-Azide plates for click-chemistry as well as Streptavidin and Neutravidin coated plates.

PolyAn’s surfaces are the ideal platform for binding of proteins, peptides, DNA and oligonucleotides. The 3D-Epoxy and 3D-NHS 96-well microplates are used mainly if adsorptive binding of peptides or oligonucleotides, for example, to high/medium binding surfaces is ineffective or the binding strength is not sufficient. Areas of application include detection methods such as ELISA, ELI- Spot, protein and peptide arrays and DNA binding.

Calibration tools for fluorescence imaging systems
For fluorescence based detection systems PolyAn is offering re-usable calibration tools. PolyAn’s calibration slides for cell assays are used as quality controls in a number of IVD systems for immunology applications.

Molecular Surface Engineering Services
PolyAn is able to equip almost any substrate with our reactive matrices for selective immobilization and antifouling surfaces for the reduction of cell adhesion and unspecific binding, respectively. As part of our Molecular Surface Engineering services, we offer functionalized consumable and substrate materials for OEM applications, which are tailored to specified customer requirements.