The Molecular Genomics Core facility offers researchers access to state-of-the-art genomics technology platforms, providing service and expertise in conducting genomics experiments.

DNA and RNA are molecules made up of a four-letter genetic code (nucleotides), a principle that is conserved across all living things. The human genome, encompassing the entire genetic code, comprises approximately three million nucleotide letters; each person has two copies, one copy inherited from each parent.

Genomics technologies allow researchers to decode or count specific DNA and RNA molecules to find differences that exist between normal and diseased cells. As cancer is a genetic disease caused by mutations that are either inherited or acquired during life, genomics technologies are extremely powerful tools for discovering mutations in genes implicated in cancer.

These discoveries are being translated into new diagnostic and prognostic tests, and are used to predict whether an individual will respond to a specific therapy. Such applications are enabling a more personalised treatment of cancer that increases patient survival and reduces the toxicity of cancer treatment on normal cells and tissues.